吡喹酮和吡噻硫酮(Oltipraz)是两种具有高效、耐受良好、服用方便等优点的杀血吸虫药物。本文旨在比较研究吡喹酮30mg/kg或40mg/kg单剂与吡噻硫酮35mg/kg 1天分2次服用对埃及血吸虫病的疗效。试验对象为尿卵阳性的15～20岁的尼日尔学生或士兵,并随机分为吡噻硫酮组、吡喹酮30mg/kg组及吡喹酮40mg/kg组。治疗前所有受试者在间隔24小时内作两次尿卵检查,并计算两次尿卵的几何平均值。取10ml尿液经微孔滤纸过滤,然后用卢戈氏 Praziquantel and Oltipraz are two schistosomiasis drugs that are highly effective, well-tolerated and easy to take. This article aims to compare the efficacy of praziquantel 30mg / kg or 40mg / kg single and oltipraz 35mg / kg 1 day and 2 doses of schistosomiasis in Egypt. The subjects were urine-egg-positive Niger students or soldiers 15 to 20 years of age and were randomly assigned to oltipraz, 30 mg / kg praziquantel and 40 mg / kg praziquantel. Before treatment, all subjects underwent urine egg examination twice within 24 hours and calculated the geometric mean of two urine eggs. Take 10ml urine through the microporous filter paper, and then Lugol’s