定喘宁是中药复方制荆,主要由葶苈子,青皮、陈皮等七味中药配制而成,对支气管哮喘有显著疗效。为探讨其作用原理,作者采用异型蛋白腹腔注射法复制豚鼠局部速发超敏反应模型。用WX—758B型微循环显微镜动态观察、定喘宁对豚鼠肠系膜超敏反应时微循环的影响,以及用72型分光光度计,波长620nm,测定肠壁伊文思蓝的含量。以了解定喘宁对局部超敏反应豚鼠肠壁血管通透性的影响。结果无论镜下所见或光电比色定 Dingchuanning is a traditional Chinese medicine compound made by the preparation of seven Chinese herbal medicines such as wolfberry fruit, green skin, dried tangerine peel and so on. It has a significant effect on bronchial asthma. In order to investigate its principle of action, the authors used atypical protein intraperitoneal injection to replicate a local hypersensitivity model in guinea pigs. The microcirculation of the mesenteric hypersensitivity of guinea pigs was observed by dynamic microscopy of WX-758B microcirculation microscope, and the content of Evans blue in the intestine wall was measured with a 72 spectrophotometer at a wavelength of 620 nm. To understand the effect of Dingchuanning on vascular permeability of guinea pig intestinal wall with local hypersensitivity. Results whether seen under the microscope or photoelectric colorimetry