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目的:探讨颈动脉狭窄复合手术（颈动脉内膜剥脱术联合血管内治疗）术后并发症及其相关因素。方法:回顾性收集2016年1月—2018年7月在北京天坛医院经复合手术行颈动脉血运重建的53例患者临床资料，从病历系统中获取个人基本信息、手术时长、术中麻醉管理、术后并发症、ICU停留时间、住院时长、住院费用等相关信息；主要结局指标采用复合终点指标，即发生术后任何一种重要器官并发症，次要结局指标为住院时长、ICU停留时间、住院费用。应用易侕统计软件与R软件对术后并发症及相关因素进行统计分析。结果:颈动脉血运重建成功率94.3%。术后10例（18.87%）出现神经系统并发症，4例（7.55%）出现呼吸系统并发症，2例（3.77%）发生心脏并发症，1例（1.89%）出现肾脏并发症，合计13例（24.53%）患者发生术后重要器官并发症。术后并发症组患者年龄[中位数，67.0（63.0，76.0）岁]显著高于无术后并发症组[61.0（55.0，66.5）岁]，差异有统计学意义（n P=0.005）。对术后重要器官并发症的相关因素进行单因素分析，结果提示年龄可能影响患者术后重要器官并发症的发生率（n P=0.010），比值比（odds ratio，OR）=1.13（95%CI 1.03~1.24）。调整混杂因素后，全凭静脉麻醉（total intravenous anesthesia, TIVA）组中年龄是术后重要器官并发症的独立危险因素（OR=1.20，95%CI 1.02~1.42），而静吸复合麻醉组中年龄不影响术后重要器官并发症的发生率。n 结论:经复合手术平台行颈动脉血运重建具有较高的成功率，TIVA时年龄是术后重要器官并发症的独立危险因素，而静吸复合麻醉时年龄不影响术后重要器官并发症的发生率。“,”Objective:To investigate the complications and related factors after carotid artery reconstruction (carotid endarterectomy combined with endovascular treatment) in the hybrid operating room (HOR).Methods:A total of 53 patients who underwent carotid artery reconstruction in Beijing Tiantan Hospital from January 2016 to July 2016 were selected and their clinical data were retrospectively collected. The following information was obtained from medical record system: general information, operation time, intraoperative anesthesia management, postoperative complications, the length of intensive care unit (ICU) stay, the length and expense of hospitalization stay. The primary outcome was a composite endpoint, that is, the occurrence of any major postoperative complication. The secondary outcomes included the length of hospitalization stay, and the length and expense of ICU stay. EmpowerStats and R software were used for statistical analysis.Results:The success rate of carotid artery revascularization was 94.3%. There were 10 cases (18.87%) of neurological complications, 4 cases (7.55%) of respiratory complications, 2 cases (3.77%) of cardiac complications, and 1 case (1.89%) of renal complications, with 13 cases (24.53%) of major postoperative complications in total. The age of patients in the postoperative complication group [median age: 67.0 (63.0-76.0) years old] was significantly higher than that in the non-postoperative complication group [median age: 61.0 (55.0-66.5) years old], and the difference was statistically significant (n P=0.005). The univariate analysis suggested that age may be a risk factor of major postoperative complications (n P=0.010), odds ratio (OR)=1.13 [95%CI 1.03-1.24]. The multiple regression analysis showed that after adjustment of confounding factors, age was an independent risk factor of major postoperative complications in the total intravenous anesthesia (TIVA) group, OR=1.20 (95%CI 1.02-1.42), while age was not a risk factor of major postoperative complications in the combined intravenous and inhalation anesthesia group.n Conclusions:Carotid artery reconstruction performed in HOR has a high success rate of vascular recanalization. Age is an independent risk factor of major postoperative complications during TIVA, while age is not a risk factor of major postoperative complications in the combined intravenous and inhalation anesthesia group.