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对随机挑选的25例荧光定量PCR检测HBV-DNA阳性的乙肝患者,进行乙肝病毒(HBV)基因分型,并分析其与乙肝血清标记物及谷丙转氨酶之间的关系。结果检出HBV B型5例,占20.00%;C型16例,占64.00%;非B非C型4例,占16.00%。B型HBeAg阳性率为40.00%,C型HBeAg阳性率93.75%,B、C型谷丙转氨酶阳性率分别为20.00%和37.50%。结果表明,乙肝病人HBV感染以C型为主,且C型感染者HBeAg阳性率比B型感染者高。C型HBV可能与HBV复制有相关性。
Twenty-five cases of hepatitis B virus (HBV) -positive hepatitis B (HBV) were randomly selected by real-time quantitative PCR for genotyping of hepatitis B virus (HBV) and its relationship with hepatitis B serum markers and alanine aminotransferase. Results HBV B type was detected in 5 cases (20.00%), type C in 16 cases (64.00%) and non-B non-C type in 4 cases (16.00%). The positive rate of type B HBeAg was 40.00%, the positive rate of type C HBeAg was 93.75%, and the positive rates of type B and C transaminases were 20.00% and 37.50% respectively. The results showed that HBV infection in hepatitis B patients with C-based, and C-positive HBeAg-positive rate higher than those infected with B-type. C-type HBV may be related to HBV replication.