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目的了解新生儿TORCH感染的早期诊断以及在新生儿科的感染情况及临床特点。方法对320例可疑新生儿进行静脉采血,应用电化学发光法对标本进行TORCH感染病原体弓形虫(TOX)、单纯疱疹病毒(HSV)、巨细胞病毒(CMV)和风疹病毒(RV)抗体检测。结果 320例住院新生儿中CMV感染14例(4.38%),RV感染10例(3.13%),HSV感染6例(1.88%),TOX感染5例(1.56%),TORCH总感染率为10.94%(35/320)。结论 TORCH感染对新生儿危害极大,其中以CMV感染占比例最大,RV感染次之。所以在新生儿疾病的诊疗过程中,应在诊断的基础上,及早做TORCH-Ig M检测,更有针对性地对症治疗,从而减少后期并发症的发生。
Objective To understand the early diagnosis of neonatal TORCH infection and neonatal infection and clinical features. Methods Venous blood samples were collected from 320 suspected neonates. Toxoplasma gondii (TOX), herpes simplex virus (HSV), cytomegalovirus (CMV) and rubella virus (RV) antibodies were detected by electrochemiluminescence. Results Among 320 hospitalized neonates, 14 (4.38%) were CMV infection, 10 (3.13%) were RV infection, 6 (1.88%) were HSV infection and 5 (1.56%) were TOX infection. The total infection rate of TORCH was 10.94% (35/320). Conclusion TORCH infection is extremely harmful to the newborn, of which CMV infection accounts for the largest proportion, followed by RV infection. Therefore, in the diagnosis and treatment of neonatal diseases, should be based on the diagnosis, as early as TORCH-Ig M testing, more symptomatic treatment, thereby reducing the incidence of late complications.