炎症性肠疾病(IBD)主要指克罗恩病(CD)和溃疡性结肠炎(UC),是一种遗传因素、环境因素和免疫因素共同参与的肠道持续性炎症疾病。大量的研究显示肠道黏膜免疫机制紊乱是IBD发病的重要机制。近年来,IBD的免疫学发病机制研究取得了很大进展,而且炎症性肠疾病的免疫学治疗也取得了 Inflammatory bowel disease (IBD) mainly refers to Crohn’s disease (CD) and ulcerative colitis (UC). It is a persistent intestinal inflammatory disease involving genetic factors, environmental factors and immune factors. A large number of studies have shown that intestinal mucosal immune disorder is an important mechanism of IBD pathogenesis. In recent years, IBD has made great progress in the study of immunological pathogenesis, and immunological treatment of inflammatory bowel disease has also been made