迄今,慢性粒细胞白血病(慢粒)的染色体改变主要为一条22号染色体的长臂末端与9号染色体的长臂末端平衡易位,即所谓ph′染色体。我们在一例患者的周围血及骨髓中发现一条22号染色体的短臂缺失,并对其家系进行了细胞遗传学研究。现报告如下: 病例报告患儿男性,7岁。10个月时因发热、腹泻在本院就医,当时体检,贫血貌,肝肋下3cm,脾肋下6cm;RBC 3.56×10~(12)/L、Hb 97g/L,网 To date, the chromosomal alterations in CML have been mainly the equilibrium translocations of the long arm end of chromosome 22 and the long arm end of chromosome 9, the so-called ph ’chromosome. We found a short arm deletion of chromosome 22 in the peripheral blood and bone marrow of a patient and performed a cytogenetic study of his family. The report is as follows: Case Report Male children, 7 years old. 10 months due to fever, diarrhea in our hospital for medical treatment, was physical examination, anemia appearance, liver ribs 3cm, spleen ribs 6cm; RBC 3.56 × 10-12 / L, Hb 97g / L,