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目的:研究常州地区普通妇女人群中HPV感染状况,为宫颈癌的预防及治疗提供理论依据。方法:采用PCR与基因芯片技术,对常州地区参加妇科体检的744名妇女进行HPV分型检查,并对不同分型感染情况进行统计学分析。结果:744名妇女中共检出HPV阳性者157例,感染率为21.10%。在高危型HPV感染妇女中,共计83.64%的妇女感染了以下六种亚型,依次是16型46例,58型28例,33型24例,18型18例,31型11例以及52型11例。结论:鉴于高危型HPV与宫颈癌发生的密切关系,对普通妇女人群展开HPV检测具有预防与治疗意义。
Objective: To study the status of HPV infection among ordinary women in Changzhou area and to provide a theoretical basis for the prevention and treatment of cervical cancer. Methods: A total of 744 women who took part in gynecological examinations in Changzhou were genotyped by PCR and gene chip technique. The genotypes of different genotypes were analyzed statistically. Results: Of the 744 women, 157 were detected positive for HPV, the infection rate was 21.10%. Among the women with high-risk HPV infection, a total of 83.64% of the women were infected with the following six subtypes: 46 cases of type 16, 28 of 58, 24 of 33, 18 of 18, 11 of 31 and 52 11 cases. Conclusion: In view of the close relationship between high-risk HPV and cervical cancer, it is of preventive and therapeutic significance to detect HPV in common women.