遗传性痉挛性截瘫是一种罕见病,国内仅报告三个家族,我们经15年观察一个家族三代23人患病,现报告如下。 资料 先症者 女,5岁。母孕及分娩正常。一向不能站立,至2岁半始能靠上肢双肘触地爬行,使身体向前移动。大小便正常。检查:发育良好,身高102cm。上肢正常,双 Hereditary spastic paraplegia is a rare disease, only three families have been reported in the country, and we have observed 23 cases of one family and three generations of illness after 15 years. The report is as follows. Information first female, 5 years old. Mother’s pregnancy and childbirth normal. Can not always stand, to 2 years and a half can rely on upper limb elbows to crawl, so that the body move forward. Normal urine. Check: well-developed, height 102cm. Upper extremity normal, double