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目的评价不满意标本对病变检出率的影响。方法选择13205例行新柏氏液基细胞学宫颈检查病例,将其中的1770例不满意标本用冰醋酸进行重新处理,对重处理仍不满意者重新取材,至制片满意后再次判读。结果重新处理后,不满意率由13.4%下降到1.43%,下降了11.97%。重处理组与标本满意未处理组比较病变检出率无显著性差异,但高度病变以上的检出率重处理组有大于未处理组的趋势。重取材组各级别病变检出率均显著高于重处理组和未处理组(P<0.05)。结论宫颈病变可导致液基细胞学取材制片不满意率增加,应重视对不满意标本的重新处理或重取材,提高宫颈病变的检出率。
Objective To evaluate the effect of unsatisfied specimens on the detection rate of lesions. Methods A total of 13205 patients with neo-Burke’s liquid-based cervical cytology were enrolled. Among them, 1770 unsatisfactory samples were reprocessed with glacial acetic acid. Those who were still dissatisfied with the re-treatment were re-drawn until the tablets were satisfactory. After the results were reprocessed, the rate of dissatisfaction decreased from 13.4% to 1.43%, a decrease of 11.97%. There was no significant difference in the detection rate of lesions between the untreated group and the untreated group, but the detection rate of the above-mentioned high-grade lesions was higher than that of the untreated group. The detection rate of lesions at all levels in the heavy material group was significantly higher than those in the heavy and non-treated groups (P <0.05). Conclusion Cervical lesions can lead to the increase of dissatisfaction rate of liquid-based cytology film production, should pay attention to the re-processing or re-drawing of the unsatisfactory specimens to improve the detection rate of cervical lesions.