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我院自一九八九年十一月以来用足叶乙甙、(VP_(16--213))安乐霉素(ACMA)为主的联合方案治疗28例难治性及复发性急性白血病,疗效结果报告如下: 材料与方法 1.病例:难治性及复发性AL28例,男性20例,女性8例,年龄21~69岁,中位年龄数40岁,全部病例均经临床、血像,骨髓像及组化染色检查确诊。(1)难治性AL13例,系指AL经VCDP、HA、DA、等常规诱导缓解方案2~4个疗程无效者。难治性急性淋巴细胞型白血病(ALL)1例,急性髓细胞型白血病(AML)12例,其中:M_11例,M_2a_2例,M_2b3例M_41例,M_5a_2例,M_5b_3例。(2)复发性ALL7例,
Our hospital since November 1989 with etoposide, (VP_ (16-213)) ampicillin (ACMA) -based combination of 28 cases of refractory and relapsed acute leukemia, The results are reported as follows: Materials and Methods 1. Case: Refractory and recurrent AL28 cases, 20 males and 8 females, aged 21 to 69 years, the median age was 40 years old, all cases were clinically, blood , Bone marrow and histochemical examination confirmed. (1) refractory AL 13 cases, refers to the AL by VCDP, HA, DA, and other conventional induced remission 2 to 4 courses of treatment were ineffective. One case was refractory acute lymphoblastic leukemia (ALL) and 12 cases was acute myeloid leukemia (AML), including M11 cases, M_2a_2 cases, M_2b3 cases M_41 cases, M_5a_2 cases and M_5b_3 cases. (2) recurrent ALL7 cases,