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目的 :观察米索前列醇用于剖宫产术中、术后减少出血的效果。方法 :选择 10 0例剖宫产者 ,随机分为米索前列醇组(米索组 ) 5 2例 ,缩宫素组 48例。米索组于术中切开子宫膀胱反折腹膜时及手术结束后于阴道后穹窿分别放置米索 2 0 0 μg。催产素组于胎儿娩出后 ,子宫体肌层注射缩宫素 2 0u。观察两组术中及术后 2 4h内阴道出血量及产后出血例数、2 4h后红色恶露持续时间。结果 :产后出血例数、术中及术后 2 4h出血量、红色恶露时间、米索组较缩宫素组明显减少 (P <0 .0 5～P <0 .0 0 1)。结论 :米索用于剖宫产可增加子宫收缩 ,减少产后出血量。
Objective: To observe the effect of misoprostol on cesarean section and postoperative bleeding reduction. Methods: One hundred and ten cases of cesarean section were randomly divided into misoprostol group (misoprostol group) 52 cases and oxytocin group 48 cases. In the misoprostol group, intraperitoneal cleavage of the peritoneal bladder was performed, and 200 μg of misoprostol was placed in the posterior fornix at the end of the operation. Oxytocin group in the fetus after delivery, uterine myometrial injection of oxytocin 20u. The intraoperative and postoperative 24 hours of vaginal bleeding and postpartum hemorrhage were observed, and the duration of red lochia after 24 hours. Results: The number of postpartum hemorrhage, intraoperative and postoperative 24 h blood loss, red lochia time and misoprostol group were significantly decreased compared with oxytocin group (P <0.05 ~ P <0.01). Conclusion: Misoprostol can increase uterine contractions and reduce the amount of postpartum hemorrhage.