用猴逆转D型病毒1型(SRV-1)接种幼龄恒河猴8只,先后出现猴艾滋病的症状和体征,以及免疫学、病毒学和病理学改变.根据猴艾滋病的病程、症状、血液、免疫功能、病毒分离、抗体出现和病变,文献上将猴艾滋病模型分为3个类型,即致死型,迁延型,恢复型.本文根据中和抗体滴度和持续病毒血症增加感染型艾滋病,并将淋巴结活检病变分为五个型,可作为病程预后的观察参考指标.猴艾滋病模型将为进一步研究猴和人艾滋病提供基础. Eight monkeys (Rhesus macaque) were inoculated with retrovirus type 1 virus (SRV-1), and the symptoms and signs of monkeys aids and the immunological, virological and pathological changes were observed successively.According to the course of disease, symptoms, Blood, immune function, virus isolation, antibody appearance and pathological changes, the monkey AIDS model has been divided into three types in the literature, namely lethal type, protracted type, restorative type.In this paper, according to neutralizing antibody titer and persistent viremia, AIDS and divide the biopsy of lymph nodes into five types, which can be used as a reference index for the prognosis of the disease.Monitoring AIDS model will provide the foundation for further research on AIDS in monkeys and humans.