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研究36例男性胃癌患者手术前血清睾酮(T)、雌二醇(E_2)和胃癌组织标本雌激素受体(EP)、孕激素受体(PR)含量.探讨胃癌的性激素水平改变及性激索与性激素受体的关系。结果表明:(1)血清睾酮、雌二醇下降是胃癌发生的危险因索,血清睾酮对胃癌患者术前评估切除可能性有参考价值.但对判断预后及复发的意义仍有待进一步研究。(2)胃癌组织中存在ER、PR受体.对ER(+)PR(+)胃癌可采用内分泌治疗。
To study the serum testosterone (T), estradiol (E2) and estrogen receptor (EP) and progesterone receptor (PR) levels in 36 patients with gastric cancer before surgery. To investigate the changes of sex hormones and sexual stimulation in gastric cancer. The relationship between cord and sex hormone receptors. The results showed that: (1) The decline of serum testosterone and estradiol is a risk factor for gastric cancer. Serum testosterone has a reference value for the possibility of preoperative evaluation of gastric cancer. However, the significance of judging prognosis and recurrence remains to be further studied. (2) ER and PR receptors are present in gastric cancer. Endocrine therapy can be used for ER (+) PR (+) gastric cancer.