论文部分内容阅读
目的:探讨肾病综合征患儿血液流变学的改变及对于血液高凝状态的治疗。方法:采用Liang-100型血液流变仪检测62名肾病综合征患儿及28名健康儿童血液流变的各项指标;服用藻酸双酯钠治疗组28例及未服用组18例的各项血液流变指标。结果:肾病综合征患儿血液高切比粘度、低切比粘度、血浆粘度均明显升高(P<0.01);服用藻酸双酯钠治疗组在低切比粘度恢复正常、水肿消失、尿蛋白转阴的时间上均明显少于未服用组(P<0.01)。结论:肾病综合征患儿常存在血液的高凝状态,藻酸双酯钠在肾病综合征的抗凝治疗中行之有效。
Objective: To investigate the changes of hemorrheology in children with nephrotic syndrome and the treatment of hypercoagulable state of blood. Methods: The indexes of hemorrheology in 62 children with nephrotic syndrome and 28 healthy children were detected by Liang-100 hemorrheology instrument. The indexes of blood rheology in 28 children who took sodium alginate and 18 children who did not take each Item blood rheology index. Results: The blood high shear rate viscosity, low shear viscosity and plasma viscosity of children with nephrotic syndrome were significantly increased (P <0.01). After taking alginate sodium, the viscosity of low nephews returned to normal, the edema disappeared and the urine Protein negative time was significantly less than the non-taking group (P <0.01). CONCLUSIONS: Hypercoagulability of blood often exists in children with nephrotic syndrome. Sodium alginate is effective in the anticoagulant therapy of nephrotic syndrome.