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目的研究血吸虫病病人唾液中特异性抗体的诊断价值。方法用间接ELISA平行检测 5 0例血吸虫病病人和 5 5例正常人 (选自非血吸虫病疫区 )唾液中IgG和IgA抗体。结果血吸虫病患者唾液中IgG与粪检的阳性符合率为 78 0 % (39/5 0 ) ,与正常对照组 3 6 % (2 /5 5 )比较 ,差异有高度显著性 (P <0 0 0 1) ,唾液中IgA与粪检的阳性符合率为 8 0 % (4 /5 0 ) ,与正常对照组 5 5 % (3/5 5 )比较 ,两者差异无显著性 (P >0 0 5 )。结论在血吸虫病患者唾液中可检测出特异性IgG抗体 ,可视为诊断血吸虫病的新途径。
Objective To study the diagnostic value of specific antibodies in saliva of patients with schistosomiasis. Methods IgG and IgA antibodies in saliva of 50 schistosomiasis patients and 55 normal controls (selected from non-schistosomiasis-endemic areas) were detected by indirect ELISA. Results The positive coincidence of IgG and fecal sera in schistosomiasis patients was 78 0% (39/5 0), which was significantly higher than that of 36% (2/5 5) of normal controls (P 0 00 The positive coincidence rate of IgA and fecal examination in saliva was 80% (4/500), but there was no significant difference between the two groups (P> 0.05) 0 5). Conclusion Specific IgG antibodies can be detected in the saliva of patients with schistosomiasis, which may be regarded as a new way to diagnose schistosomiasis.