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复制衰老最早是在体外培养的3个月人胚肺二倍体细胞中发现的一种细胞状态,它不同于细胞死亡和凋亡,被认为是体内许多年龄相关性疾病的病因。复制衰老与体外培养的细胞衰老改变有密切关系,但复制衰老与眼部组织的关系尚未明了。就复制衰老与角膜、晶状体上皮细胞(LECs)、视网膜色素上皮(RPE)细胞关系的研究进展进行综述。
Replication of senescence is the first cell state found in 3-month human embryo lung diploid cells cultured in vitro. It is different from cell death and apoptosis and is considered to be the etiology of many age-related diseases in the body. The relationship between senescence and eye tissue has not been clarified yet. The research progress on the relationship between senescence and the cornea, lens epithelial cells (LECs) and retinal pigment epithelium (RPE) cells were reviewed.