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目的 :研究胃泰胶囊的药理作用。方法 :用水杨酸诱发大鼠胃炎模型 ;用 H2 清除法及胃内容物重量分别测定正常小鼠胃血流量及胃排空 ;用二甲苯致小鼠耳肿胀 ;用皮下棉球致肉芽肿 ;用醋酸致小鼠扭体反应。胃泰胶囊内含物清膏灌胃给药。结果 :胃泰胶囊对水杨酸性胃炎有明显保护作用 ;增加正常小鼠胃血流及胃排空 ;抑制二甲苯致小鼠耳肿胀及皮下棉球肉芽增生 ;抑制醋酸引起的小鼠扭体反应。结论 :胃泰胶囊具有抗炎、镇痛、保护胃黏膜、增强胃动力等作用
Objective: To study the pharmacological effects of Weitai Capsule. METHODS: Salicylic acid induced rat gastritis model; gastric blood flow and gastric emptying of normal mice were measured by H2 clearance method and the contents of gastric contents; mouse ear swelling was induced by xylene; granuloma was caused by subcutaneous cotton ball; The writhing response of mice was induced with acetic acid. Weitai capsule content cream was given orally. RESULTS: Weitai Capsule had obvious protective effect on salicinic acid gastritis; increased gastric blood flow and gastric emptying in normal mice; inhibited xylene-induced mouse ear swelling and subcutaneous tampon granulation; inhibited acetic acid-induced writhing in mice. reaction. Conclusion : Weitai Capsule has anti-inflammatory, analgesic, gastric mucosal protection, and enhanced gastric motility