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重症急性胰腺炎(Severe Acute Pancreatitis,SAP)一种常见疾病,其病情严重,死亡了较高。患者一般存在胰腺局部与区域性的损伤表现外,同时还会伴随着肝脏、肺部、肾部等内脏器官的损害。其中,肝脏是一线血液回流的必经之路,是多种细胞因子的灭火场所,也是重症胰腺有累及的重要部位之一,肝损伤的发生率相对于其他内脏来说更高。因此,对于重症胰腺炎肝损伤的机制进行研究,对于降低SAP肝损伤发生率有着十分重大的实际意义。
Severe acute pancreatitis (Severe Acute Pancreatitis, SAP) A common disease, its condition is serious, high mortality. Patients generally have local and regional pancreatic damage performance, but also accompanied by liver, lung, kidney and other internal organs damage. Among them, the liver is the first line of blood reflux must pass through the road, is a variety of cytokines and a place of fire is also involved in severe pancreas one of the major parts, the incidence of liver damage relative to other organs is higher. Therefore, studying the mechanism of liver injury in severe pancreatitis has great practical significance for reducing the incidence of SAP liver injury.