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目的:探讨血必净对肺癌并发阻塞性肺炎患者的炎性因子的影响。方法:选取2013年10月至2014年10月就诊肺癌并发阻塞性肺炎患者48例,随机分两组各24例。对照组给予吸氧、祛痰、激素、营养支持等常规治疗,观察组给予血必净静脉滴注治疗,治疗2周,比较两组患者疗效,并分别于治疗前后测定患者炎性因子变化,包括肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)及C反应蛋白(CRP)等。结果:观察组治疗有效率明显高于对照组(P<0.05);观察组治疗后TNF-α、IL-6、CRP等水平均优于对照组(P<0.05)。结论:对肺癌并发阻塞性肺炎患者在常规治疗基础上联合血必净注射液治疗的效果较好,具有良好的抗菌作用,促进患者康复。
Objective: To investigate the effect of Xuebijing on inflammatory cytokines in patients with lung cancer complicated with obstructive pneumonia. Methods: Forty-eight patients with obstructive pulmonary disease from October 2013 to October 2014 were randomly divided into two groups of 24 patients. The control group was given routine treatment of oxygen, expectorant, hormone and nutrition support. The observation group was given Xuebijing intravenous infusion for 2 weeks. The curative effect of the two groups was compared. The changes of inflammatory factors in the two groups were measured before and after treatment. Including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and C-reactive protein (CRP) and so on. Results: The treatment efficiency in the observation group was significantly higher than that in the control group (P <0.05). The levels of TNF-α, IL-6 and CRP in the observation group were better than those in the control group (P <0.05). Conclusion: The treatment of patients with obstructive pulmonary disease with obstructive pulmonary disease on the basis of routine treatment combined with Xuebijing injection has a good effect, has good antibacterial activity, and promote patient rehabilitation.