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目的观察儿童消化性疾病的病理变化及其与HP感染的关系。方法选择60例年龄在14～17岁有反复腹痛、呕吐、吐血、纳差等症状的患儿,通过胃镜检查,观察其消化道形态变化,并取胃粘膜进行病理检测和HP检测,并根据HP检查结果随机分为HP阳性组及HP阴性组。结果 HP阳性胃粘膜炎症反应程度明显严重,于HP阴性组(p<0.05);儿童上消化道疾病与HP关系密切。结论儿童上消化道疾病患儿胃粘膜炎症反应程度与HP感染明显相关。
Objective To observe the pathological changes of children with digestive diseases and their relationship with HP infection. Methods Sixty children aged 14-17 years old with recurrent abdominal pain, vomiting, vomiting blood and anorexia were selected. Gastroscopy was used to observe the morphological changes of the digestive tract. The gastric mucosa was taken for pathological examination and HP detection. HP test results were randomly divided into HP positive group and HP negative group. Results The positive reaction of HP positive gastric mucosa was severe in HP negative group (p <0.05). Child upper gastrointestinal disease was closely related to HP. Conclusion Gastric mucosal inflammatory response in children with upper gastrointestinal diseases is significantly associated with HP infection.