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作者应用5-氟脲嘧啶栓剂作直肠癌手术前治疗,以降低局部复发和转移。5-氟脲嘧啶能杀灭癌细胞并使其对放射线敏感,而栓剂的局部药物浓度较静脉给药为高,故可在门诊应用,并能提高术前放射治疗的疗效,作者共计使用于50例。材料和方法:将5-氟脲嘧啶溶于Witepsol栓基
The authors used 5-fluorouracil suppository for preoperative treatment of rectal cancer to reduce local recurrence and metastasis. 5-Fluorouracil can kill cancer cells and make them sensitive to radiation. The local concentration of suppositories is higher than that of intravenous administration. Therefore, it can be used in outpatient clinics and can improve the efficacy of preoperative radiation therapy. 50 cases. Materials and Methods: Dissolve 5-fluorouracil in Witepsol plug