肝脏疾患特别是晚期肝病或肝功能衰竭时,常同时累及肾脏功能。1932年Helwig氏首先将胆道手术后并发急性肾功能衰竭者命名为“肝肾综合症”,嗣后即广泛用于各种同时有肝肾损害的疾病。现今认为:此名词运用相当混乱,甚多不妥之处。“肝肾综合征”一词实际系指肝硬化(有人认为还包括暴发型肝炎)病人在肝功能代偿失调期发生少尿,无尿、氮质血症以及肾小球滤过率、肾血流量减少为主的肾功能不全,而无原发性器质性肾脏病,肾脏本身无明显病理变化。1969年Koppel将死于“肝肾综合征”的病人的肾脏移植给慢性尿毒症患者,移植的肾脏得到了迅速而良好的恢 Liver disorders, especially in advanced liver disease or liver failure, often involve both kidney function. 1932 Helwig’s first after biliary surgery complicated with acute renal failure were named “hepatorenal syndrome”, then that is widely used in a variety of diseases with liver and kidney damage. Now think: This term is quite chaotic, many inappropriate. The term “hepatorenal syndrome” actually refers to oliguria, anuria, azotemia and glomerular filtration rate in patients with cirrhosis (some believe fulminant hepatitis) in decompensated liver function, kidney Blood flow-based renal insufficiency, without primary organic kidney disease, the kidney itself has no significant pathological changes. In 1969, Koppel’s kidney transplant from patients with “hepatorenal syndrome” to patients with chronic uremia gave a prompt and good recovery