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盐酸丙卡特罗(procaterol)是第三代新的拟交感β_2受体兴奋剂,其化学名为5—(1—羧基—2—异丙胺基丁基)—8—羧基—奎诺酮盐酸盐半水合物,分子式C_(16)H_(22)N_2O_3.HCI·1/2H_2O。对气管平滑肌的β_2受体有较高的选择性,而对心脏的兴奋性较弱。中国天津大冢制药有限公司生产的丙卡特罗片剂(商品名MEPTIN)已经在我国临床使用,对支气管哮喘及喘息性支气管炎有较好的疗效,但国产的丙卡特罗片尚未见报道。现就国产盐酸丙卡特罗片临床观察情况报告如下。
Procaterol hydrochloride is the third generation of a new sympathomimetic beta_2 receptor agonist whose chemical name is 5- (1-carboxy-2-isopropylaminobutyl) -8-carboxy-quinolone hydrochloride Salt hemihydrate, molecular formula C_ (16) H_ (22) N_2O_3.HCI · 1 / 2H_2O. The tracheal smooth muscle β_2 receptor has a high selectivity, while the excitability of the heart is weak. Procaterol tablets produced in Tianjin, China Otsuka Pharmaceutical Co., Ltd. (MEPTIN) have been used clinically in our country and have a good effect on bronchial asthma and asthmatic bronchitis. However, the domestic procaterol tablets have not been reported yet. Now on the domestic production of procaterol hydrochloride clinical observations are as follows.