临床上雷公藤甲素用于白血病的治疗。雷公藤甲素分子中的内酯环易水解失效,水解产物毒性较大。我们探讨了不同pH值和光照对雷公藤甲素水溶液含量的影响。取12个25ml的容量瓶,各加入200μg/ml的雷公藤甲素水溶液1ml,用缓冲液配制的pH1～12的溶媒调至刻度,混匀,再测pH值。于45±1℃恒温,分别在 Triptolide is clinically used for the treatment of leukemia. The lactone ring in triptolide molecules is prone to hydrolysis failure and the hydrolysis product is more toxic. We investigated the effect of different pH values ​​and light on the content of triptolide in aqueous solution. Take 12 25 ml volumetric flasks, add 200 μg/ml each of triptolide solution 1 ml, adjust the pH 1-12 medium prepared with buffer to the mark, mix, and then measure the pH. Constant temperature at 45±1°C, respectively