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胃动素(motilin,MTL)是一种与消化道运动有关的多肽激素。通过血液MTL浓度的观察,已阐明了MTL与消化过程及某些消化道疾病有密切关系。为研究胃液中MTL浓度对疾病的诊断意义,我们观察了浅表性胃炎、胃溃疡、十二指肠溃疡、萎缩性胃炎、胃癌等患者胃液中胃动素浓度。同时测定胃液中癌胚抗原(carcino-embryonic antigen,CEA)浓度,探讨了它们与消化道疾病的关系及临床诊断价值。
Motilin (MTL) is a polypeptide hormone associated with gastrointestinal motility. Through the observation of blood MTL concentration, it has been clarified that MTL is closely related to the digestive process and some gastrointestinal diseases. To investigate the diagnostic value of MTL concentration in gastric juice on the disease, we observed motilin concentrations in gastric juice in patients with superficial gastritis, gastric ulcer, duodenal ulcer, atrophic gastritis and gastric cancer. The carcinoembryonic antigen (CEA) concentrations in gastric juice were measured simultaneously, and their relationship with gastrointestinal diseases and clinical diagnostic value were also discussed.