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目的 :探讨18F-脱氧葡萄糖(FDG)PET/CT最大标准摄取值(SUVmax)在预测宫颈癌组织类型及分化差异中的应用价值。方法:回顾性分析59例未经任何治疗的宫颈癌患者18F-FDG PET/CT显像资料,所有患者均经活检或手术病理证实,其中鳞癌患者49例,腺癌患者10例,且高分化9例,中分化32例,低分化18例,并对所有宫颈癌原位病灶SUVmax进行分析,探讨SUVmax与宫颈癌组织类型、分化程度之间的关系。结果:59例宫颈癌患者宫颈原发病变的SUVmax为10.95±4.96,腺癌组SUVmax为5.98±3.12,鳞癌组SUVmax为12.32±5.12,2组SUVmax差异有统计学意义(P<0.05),高分化组SUVmax为6.21±4.12,中分化组SUVmax为10.15±5.72,低分化组SUVmax为16.12±6.11,3组差异有统计学意义(P<0.05)。结论 :SUVmax与宫颈癌组织类型及分化程度存在一定的关系,SUVmax能一定程度上提示宫颈癌预后。
Objective: To investigate the value of 18F-FDG PET / CT maximum ingesting value (SUVmax) in predicting the type and differentiation of cervical cancer. Methods: The data of 18F-FDG PET / CT in 59 cases of cervical cancer without any treatment were retrospectively analyzed. All patients were confirmed by biopsy or surgical pathology, including 49 cases of squamous cell carcinoma and 10 cases of adenocarcinoma 9 cases were differentiated, 32 cases were moderately differentiated and 18 cases were poorly differentiated. The SUVmax of all cervical cancer in situ lesions were analyzed to explore the relationship between SUVmax and the type and differentiation of cervical cancer. Results: The SUVmax of primary cervical lesions in 59 cases of cervical cancer was 10.95 ± 4.96, that of adenocarcinoma was 5.98 ± 3.12, that of squamous cell carcinoma was 12.32 ± 5.12, there was significant difference between the two groups (P <0.05) SUVmax was 6.21 ± 4.12 in the well-differentiated group, 10.15 ± 5.72 in the moderately differentiated group, and 16.12 ± 6.11 in the poorly-differentiated group (P <0.05). Conclusion: There is a certain relationship between SUVmax and the type and differentiation of cervical cancer. SUVmax can prompt the prognosis of cervical cancer to some extent.