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目的了解广州市海珠区1～59岁人群乙型肝炎病毒感染情况,为乙肝防制提供科学依据。方法应用ELISA对1～59岁600例居民进行乙肝5项标志物检测。结果海珠区居民HBV感染率为40.83%;HBsAg阳性率为6.33%,不同年龄组间差异有统计学意义;抗-HBs阳性率为65.00%,不同年龄组间差异有统计学意义;HBVM全阴率为22.33%,不同年龄组间差异有统计学意义。成年人的乙肝疫苗接种率较低。结论1～59岁人群中HbsAg携带率处于中等水平,免疫保护水平需进一步提高,易感者多,建议继续加强儿童、青少年的乙肝疫苗查漏补种工作,对青壮年、老年人群,应加强乙肝疫苗接种工作。
Objective To understand the status of hepatitis B virus infection among 1-59 years old people in Haizhu District of Guangzhou City and provide a scientific basis for hepatitis B prevention and control. Methods Five markers of hepatitis B were detected in 600 residents from 1 to 59 years old by ELISA. Results The prevalence of HBV infection was 40.83% in Haizhu district, the positive rate of HBsAg was 6.33%, the difference was statistically significant among different age groups. The positive rate of anti-HBs was 65.00%, with significant difference between different age groups. Rate was 22.33%, the difference between different age groups was statistically significant. Hepatitis B vaccination rates in adults are low. CONCLUSIONS: The prevalence of HbsAg in the population aged 1-59 is at a moderate level, and the level of immune protection needs to be further improved with more susceptible persons. It is suggested that the investigation of hepatitis B vaccine should be further enhanced in children and adolescents, and should be strengthened for young adults and elderly people Hepatitis B vaccination work.