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目的分析2004~2009年东莞市45例8个月以内住院的婴儿麻疹病例进行临床特征。方法分折45例8月龄以下婴儿麻疹病例进行流行病学特征、临床特点。结果 45例病例均经麻疹IgM抗体检测阳性而确诊,患儿均是外来流动人口子女,以6~8月婴儿为主,占60%;1~6月发病者占77.8%;临床表现以中高热为主,占88.9%,发热后第2~3d出疹者,占73.3%,有合并肺炎者占33.7%,腹泻者占20%,绝大部分白细胞计数正常。结论随着儿童麻疹疫苗预防接种工作的加强,麻疹发病有向8月龄以下婴儿发展趋势,在婴儿出现发热伴出疹就诊时应作麻疹IgM抗体检测,提高易感人群麻疹疫苗接种率是降低婴儿麻疹发病率的有效措施。
Objective To analyze the clinical characteristics of 45 measles infants who were hospitalized within 8 months from 2004 to 2009 in Dongguan City. Methods 45 cases of infants aged less than 8 months measles epidemiological characteristics, clinical features. Results All the 45 cases were diagnosed by measles IgM antibody test. The children were migrant children, accounting for 60% of the infants in June to August. The incidence rate was 77.8% in 1 to 6 months. The clinical manifestations were as follows: High fever, accounting for 88.9%, 2 to 3d after fever rash, accounting for 73.3%, with pneumoconiosis accounted for 33.7%, diarrhea accounted for 20%, the vast majority of normal white blood cell count. Conclusions With the improvement of vaccination against measles in children, the incidence of measles has a tendency to infants under 8 months of age. Measles IgM antibodies should be detected in the infants with fever and rash and the vaccination rate of measles in susceptible population should be reduced Effective measles incidence in infants.