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应用放射免疫测定法对61例喉癌病人、3例喉良性肿瘤病人及40例正常人进行了血清T_3,T_4及TG的测定。结果发现:喉癌病人血清T_3值明显低于正常人(P<0.01),T_4值则较正常人略升高,但P>0.05。TG值与正常人无区别。喉部良性肿瘤病人的血清T_3,T_4及TG与正常人无差异。在T_3下降的喉癌患者中,经手术治疗后,T_3值随病情的好转有所恢复,但对术后并发咽瘘者则相反。然而,应用甲状腺素可使咽痊愈合加速。提示:喉癌患者血清T_3的测定,有助于观察病情变化,并为治疗提供参考。
Radioimmunoassay was used to detect serum T_3, T_4 and TG in 61 patients with laryngeal cancer, 3 patients with benign laryngeal tumors, and 40 normal controls. The results showed that the serum T_3 value of patients with laryngeal cancer was significantly lower than normal (P <0.01), T_4 value was slightly higher than normal, but P> 0.05. The TG value is no different from normal people. Serum T_3, T_4 and TG levels in patients with benign laryngeal tumors were not different from those in normal controls. In patients with laryngeal cancer with decreased T_3, T_3 values recovered with improvement of the disease after surgery, but it was the opposite for postoperative pharyngeal spasm. However, the use of thyroxine can accelerate the healing of pharyngeal hernia. Tip: Determination of serum T_3 in patients with laryngeal cancer is helpful to observe the changes in conditions and provide reference for treatment.