论文部分内容阅读
目的:探讨吸入糖皮质激素联合储雾罐治疗5岁以下喘息性患儿的临床疗效。方法:选取124例急性喘息性疾病患儿(0~5岁)为研究对象,根据随机数字表将患儿分为吸入性糖皮质激素联合雾化器治疗组(A组)以及吸入性糖皮质激素联合储雾罐治疗组(B组)各62例,对比分析两组患儿治疗依从性、临床疗效及肺功能改善情况。结果:A组患儿依从率为53.22%,B组患儿依从率为85.48%,两组患儿依从率具有统计学差异(P<0.05)。A组总有效率为77.42%,B组总有效率为93.55%,差异有统计学意义(P<0.05)。A组气促缓解时间、咳嗽消失时间、哮鸣音消失时间、平均住院时间显著长于B组,而家属满意度低于B组,差异有统计学意义(P<0.05)。B组患儿治疗5天后第1 s用力呼吸容积(FEV1)、最大呼气峰流速(PEF)以及第1 s呼吸气体的容积与用力肺活量的比值(FEV1/FVC)显著高于A组,差异有统计学意义(P<0.05)。结论:吸入糖皮质激素联合储雾罐治疗儿童喘息性疾病可有效提高患儿耐受性及依从性,提高患儿治疗效果,改善患儿临床症状及肺功能,促进患儿预后。
Objective: To investigate the clinical efficacy of inhaled glucocorticoid combined with aerosol canister to treat asthmatic children under 5 years of age. Methods: A total of 124 children with acute asthmatic disease (aged 0-5 years) were enrolled in this study. According to the random number table, children were divided into inhaled glucocorticoid combined nebulizer group (group A) and inhaled glucocorticoids Hormone combined with the storage tank treatment group (B group) of 62 cases, comparative analysis of two groups of children compliance, clinical efficacy and improvement of lung function. Results: The compliance rate of children in group A was 53.22%. The compliance rate of children in group B was 85.48%. There was significant difference (P <0.05) between two groups. The total effective rate in group A was 77.42%, and the total effective rate in group B was 93.55%, the difference was statistically significant (P <0.05). In group A, the time of relief, the disappearance of cough, the disappearance of wheeze and the average length of stay in hospital were significantly longer than those in group B, but the satisfaction of family members was lower than that in group B (P <0.05). The FEV1, PEF and FEV1 / FVC of group B were significantly higher than those of group A after treatment for 5 days (P <0.05) There was statistical significance (P <0.05). Conclusion: Inhaling corticosteroids combined with aerosol cans can effectively improve children’s tolerance and compliance, improve the therapeutic effect of children, improve the clinical symptoms and lung function, and promote the prognosis of children.