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为评价部分平均通过时间（ＭＴＴｐ）和Ｆ－Ｖ曲线形状对检查吸烟者小气道功能的临床意义，作者对１１６例被动和轻、重度主动吸烟者进行了常规肺通气功能、ＭＴＴｐ和Ｆ－Ｖ曲线形状的探讨。常规肺通气功能和Ｆ－Ｖ曲线形状用常规法测定。ＭＴＴｐ用“简易计算法”公式计算。结果显示凸型Ｆ－Ｖ曲线的分布随吸烟程度而上升。·Ｖ５０、·Ｖ２５下降及ＭＴＴ４５％～５５％、ＭＴＴ７０％～８０％延长在凸型与重度吸烟组一致。ＭＴＴ４５％～５５％与ＭＴＴ７０％～８０％延长的范围在两者都是预计值的１１０％～１２０％，表明小气道功能已有轻度障碍。因而凸型Ｆ－Ｖ曲线、ＭＴＴ４５％～５５％及ＭＴＴ７０％～８０％延长、·Ｖ５０、·Ｖ２５下降都是检查小气道功能的敏感指标。用“简易计算法”计算ＭＴＴｐ简便准确，宜于临床推广应用
To evaluate the clinical significance of partial mean transit time (MTTp) and F-V curve shape in examining small airway function in smokers, the authors performed routine pulmonary ventilation on 116 passive and mild-to-moderate active smokers, and MTTp and F-V Discussion of Curve Shape. Conventional pulmonary ventilation and F-V curve shapes were routinely determined. MTTp is calculated using the “simple calculation method” formula. The results showed that the distribution of convex F-V curves increased with the degree of smoking. · V50, · V25 decline and MTT 45% ~ 55%, MTT 70% ~ 80% extended in the convex and severe smoking group. The range of 45% -55% MTT and 70% -80% MTT extension was between 110% and 120% of the expected value for both, indicating mild dysfunction in small airway function. Thus convex F-V curve, MTT45% ~ 55% and MTT70% ~ 80% extension, V50, · V25 decline are sensitive indicators of small airway function. Using “simple calculation method” to calculate MTTp simple and accurate, suitable for clinical application