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为了解人乳头瘤病毒 (HPV)感染与宫内节育器 (IUD)及 HPV感染的危险因素之间的关系 ,应用HPV6、11型和 HPV16、18型两对引物 ,通过聚合酶链反应 (PCR)技术 ,对 2 5例未置 IUD和 93例置 IUD妇女者的宫颈拭子进行 HPV- DNA的检测。结果 :选择的 118例妇女宫颈拭子的 HPV检出率为 40 .6 8%。其中未置 IUD组、O型环组和 T型环组 (TCu IUD)的 HPV检出率分别为 2 4.0 0 %、37.0 4%和 5 6 .41%。多因素 logistic回归平衡各因素间的作用 ,达到显著意义的因素有 TCu IUD、宫颈糜烂 ,子宫异常出血和阴道炎 ,其 OR值分别为 4.2 6 3、2 .6 86、4.5 38和 3.414。HPV感染与 IUD的类型有关 ,TCu IUD是 HPV感染的危险因素 ,其他危险因素是宫颈糜烂、子宫异常出血和阴道炎
In order to understand the relationship between human papillomavirus (HPV) infection and risk factors of IUD and HPV infection, two pairs of HPV6, 11 and HPV16, ) Technique was used to detect HPV-DNA in cervical swabs of 25 non-IUD and 93 IUD women. Results: The detection rate of HPV in 118 women selected for cervical swab was 40.68%. The detection rate of HPV without IUD group, O-ring group and TCu IUD group was 240.0%, 37.0 4% and 56.41% respectively. Multivariate logistic regression to balance the role of various factors, to achieve significant factors TCu IUD, cervical erosion, abnormal uterine bleeding and vaginitis, the OR values were 4.2 6 3,2 .6 86,4.5 38 and 3.414. HPV infection and the type of IUD, TCu IUD is a risk factor for HPV infection, other risk factors are cervical erosion, abnormal uterine bleeding and vaginitis