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目的探讨纳络酮合并清开灵注射液治疗COPD并发肺性脑病的疗效。方法将确诊为COPD并发肺性脑病的48例患者,随机分为治疗组(用纳络酮+清开灵注射液治疗)28例和对照组(常规方法治疗)20例,观察两组患者治疗后的好转率。结果治疗组总有效率为85.7%,对照组为60%,两组比较差异有统计学意义(P<0.05)治疗组明显优于对照组。在治疗过程中无明显不良反应。结论纳络酮合并清开灵注射液治疗肺性脑病有明显的近期疗效。
Objective To investigate the efficacy of naloxone combined with Qingkailing injection in the treatment of pulmonary encephalopathy in patients with COPD. Methods Forty-eight patients diagnosed as COPD with pulmonary encephalopathy were randomly divided into treatment group (naloxone + Qingkailing injection) 28 cases and control group (conventional treatment) 20 cases, the treatment of two groups were observed After the improvement rate. Results The total effective rate was 85.7% in the treatment group and 60% in the control group. The difference between the two groups was statistically significant (P <0.05). The treatment group was significantly better than the control group. No significant adverse reactions in the course of treatment. Conclusion Naloxone combined QingQingLing injection in the treatment of pulmonary encephalopathy have obvious short-term curative effect.