阿苯达唑对实验大鼠体内华支睾吸虫体壁和肠管影响的超微结构观察结果表明,该药对虫体皮层和肠绒毛,在给药1h即出现皮层突起肿胀、粘连和肠绒毛肿胀,其内的点线模糊不清。给药24h损害已相当严重,皮层突起出现坏死、崩溃,部分肠绒毛溶解、坏死。而且皮层和肠管损害的发生发展过程是同步的。可以认为阿苯达唑是通过对皮层和肠管的双重损害,进而影响其生理机能,使虫体死亡的。 The ultrastructure observation of albendazole on the body wall and intestine of C. sinensis in experimental rats showed that the drug showed swelling, adhesion and villus on the cortex and intestinal villi Swelling, the dotted lines within the ambiguous. Dosing 24h damage has been quite serious, cortical processes appear necrosis, collapse, partial villus villi, necrosis. And the development of cortical and intestinal damage is synchronous. Albendazole can be considered through double damage to the cortex and intestine, thereby affecting its physiological function, so that the death of the parasite.