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Levy 等于1975年报告,早期胃恶性肿瘤患者胃液中分泌性免疫球蛋白 A(SIgA)含量显著增高,认为这是宿主对胃肠管恶性细胞的局部免疫反应,故胃液 SIgA 测定可作为早期胃癌的一种新的诊断试验。为验证胃液 SIgA 测定在胃癌诊断,特别是早期诊断上的实用价值,我们于1979年结合胃癌普查工作,对普查人群中的490例进行胃液 SIgA 测定,并随访二年,今将结果报告于后,以供参考。
Levy et al. (1975) reported that the level of secretory immunoglobulin A (SIgA) in gastric juice in patients with early gastric cancer was significantly higher. This is considered to be the local immune response of the host to malignant cells of the gastrointestinal tract. Therefore, SIgA measurement in gastric juice can be used as early gastric cancer. A new diagnostic test. To verify the practical value of gastric juice SIgA determination in the diagnosis of gastric cancer, especially in early diagnosis, we combined gastric cancer screening work in 1979. We performed gastric fluid SIgA determination on 490 patients in the general survey and followed up for two years. The results are reported later. ,for reference.