鼻炎和哮喘病人局部应用糖皮质激素的效能可能依赖于气道粘膜的药物滞留。使用氟替卡松丙酸酯 ,滞留可因亲脂性达到排除 ,鉴于此 ,对于布地奈德 (ｂｕｄｅｓｏｎｉｄｅ)而言也提供另外一种可能性 ,即通过其在气道内形成脂肪酸酯释放出活性药物成分。本研究的目的是确定布地奈德 Topical glucocorticoid efficacy in rhinitis and asthma patients may depend on airway mucosal drug retention. With fluticasone propionate, retention can be ruled out by lipophilicity and in view of this, there is also the possibility for budesonide to release the active pharmaceutical ingredient via its formation in the airways. The purpose of this study was to determine budesonide