目的：观察应用不同方法治疗腰椎间盘突出症的临床效果，提高对腰椎间盘突出症治疗的临床经验。方法将150例于2010年6月-2013年3月在我院接受治疗的腰椎间盘突出症患者随机分为对照组与观察组各75例，对照组患者通过常规开窗手术进行治疗，观察组患者则通过钉棒内固定手术治疗，对比两组手术方法的术中出血量、手术耗时以及住院天数，并且于术后应用Oswestry疼痛调查表评估患者症状的缓解与生活质量的改善情况，以及手术疗效。结果观察组患者的术中出血量高于对照组、手术耗时多于对照组，但住院天数少于对照组，两组比较差异显著（P<0.05）；术后2周、4周、6周患者的Oswestry评分均一定程度降低，但是观察组患者降低幅度更为显著（P<0.05）；6周后观察组治疗的优良率高于对照组，分别为92.0%和77.3%，差异显著（P<0.05）。结论钉棒内固定手术治疗腰椎间盘突出症能够显著改善患者症状、降低疼痛、促进预后，从而提高患者的生活质量，值得临床推广应用。“,”Objective To observe clinical effect of different methods in treatment of lumbar disc herniation, and improve clinical experience for the treatment of lumbar disc herniation. Methods 150 cases with lumbar disc hernination in our hospital from June 2010 to March 2013 were selected. Patients were randomly divided into control group and observation group, 75 cases in each group. Control group received conventional fenestration. Observation group received the treatment of screw and rod internal fixation system. Peri-operative bleeding, operative time and hospital days for methods in two groups were compared. Oswestry was applied in post-treatment. Oswestry was used to evaluate remission of symptoms, quality of life and curative effect. Results Peri-operative bleeding in observation group was higher than control group. Operative time in observation group was more than control group, but hospital days in observation group were less than control group. The difference is statistical y significant(P<0.05) Oswestry score for two groups dropped evenly at two weeks, four weeks and six weeks, and Oswestry score for observation group was significantly decreased(P<0.05). Total effective rate for observation group (92.0%) was obviously higher than control group (77.3%) after six weeks. Conclusion Combination treatment of chinese and western medicine in treatment of lumbar disc herniation has a higher clinical value. This therapy can significantly improve symptoms of patients, quality of life and therapeutic effect. It is worth popularizing application in clinic.