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目的观察运动对T2DM患者餐后血糖的影响,优化运动治疗处方。方法选择54例T2DM患者,采用数字随机表分为餐后非运动组与运动组,每组各27例,非运动组进行静息试验,运动组按照三因素(餐后开始运动时间A、运动持续时间B、运动强度C)三水平正交设计进行运动锻炼。以餐后150min内餐后血糖曲线下面积(AUC)为评价指标。结果 (1)运动、非运动组AUC分别是(589.66±31.89)mmol/L.min和(616.34±36.48)mmol/L.min。(2)A因素三水平(A1:餐后10min;A2:餐后20min;A3:餐后30min)中以A2最佳(P=0.018)。B因素三水平(B1:持续20min;B2:持续30min;B3:持续40min)中以B3最佳(P=0.016)。C因素的三水平(C1:4km/h速度步行,C2:6km/h速度步行,C3:8km/h速度步行)对AUC的影响差异无统计学意义(P=0.229)。结论运动可改善糖代谢,餐后20mim开始以4km/h的步行速度,运动40min可能是T2DM运动治疗的较好处方,但需个体化调节运动参数。
Objective To observe the effect of exercise on postprandial blood glucose in T2DM patients and to optimize the exercise prescription. Methods Fifty-four patients with T2DM were selected and divided into postprandial non-exercise group (n = 27) and exercise group (n = 27) by non-exercise group. The exercise group was divided into three groups according to three factors Duration B, exercise intensity C) three levels of orthogonal design for exercise. The postprandial blood meal under 150min postprandial blood glucose curve area (AUC) as the evaluation index. Results (1) The AUC of exercise group and non-exercise group were (589.66 ± 31.89) mmol / L.min and (616.34 ± 36.48) mmol / L.min respectively. (2) A factor three levels (A1: postprandial 10min; A2: postprandial 20min; A3: postprandial 30min) with A2 best (P = 0.018). B3 was the best (P = 0.016) in the three factors of level B (B1: 20 min; B2: 30 min; B3: 40 min). There was no significant difference in AUC between three factors of C (C1: 4km / h speed walk, C2: 6km / h speed walk, C3: 8km / h speed walk) (P = 0.229). Conclusion Exercise can improve glucose metabolism. After 4 months of postprandial 20mim walking speed of 4km / h, exercise 40min may be a good prescription for T2DM exercise therapy, but the individual need to regulate motor parameters.