非那西丁一般是以对硝基氯苯为原料,经乙氧基化、还原和乙酰化等步骤制得的。所得产品常含微量有机色素杂质,故在外观色泽以及进行乙氧基苯胺和易碳化物比色项目检查时,常有颜色反应,有时为微黄色,有时为暗红色。 Vinkler等报导非那西丁与氧化剂的颜色反应,系由于对氨基苯乙醚被氧化成“氨基苯乙醚红”(Phenetidine red)。我们把非那西丁粗制品中水不溶物用热水充分洗涤除去非那西丁后得到湿润时呈灰黑色,干燥时呈暗绿色的物质,易溶于有机溶剂如醋酸、乙醇和苯中,难溶于冷水微溶于沸 Phenacetin is generally based on nitrochlorobenzene as raw material, the ethoxylation, reduction and acetylation and other steps in the system. The resulting product often contains trace amounts of organic dye impurities, it is often in the appearance of color and colorimetric ethoxy ethoxyaniline and carbides check items, sometimes yellowish, sometimes dark red. Vinkler et al. Reported the phenotypic reaction of phenacetin with oxidants due to the oxidation of p-aminophenylether to Phenetidine red. We are non-phenacetin crude water insoluble material fully washed with hot water to remove phenacetin wet gray gray, dark green when dry material, soluble in organic solvents such as acetic acid, ethanol and benzene , Insoluble in cold water slightly soluble in boiling water