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5. ANTITUMOR IMMUNITY AND VACCINE EFFECT INDUCED BY IL—12 SYNERGIZES B7—1 GENE TRANSFECTED CELLS

ANTITUMOR IMMUNITY AND VACCINE EFFECT INDUCED BY IL—12 SYNERGIZES B7—1 GENE TRANSFECTED CELLS

来源 :Chinese Journal of Cancer Research | 被引量 : 0次 | 上传用户：czmallen

【摘 要】

：

Objective: To study the synergic effects of IL-12 and B7-1 transfectant on antitumor immunity in vivo. Methods: The retrovirus vector encoding mIL-12 and mB7-1

【作 者】

：

王志华 李弘 张春艳 

【机 构】

：

InstituteofOncology

【出 处】

：

Chinese Journal of Cancer Research

【发表日期】

：

2003年1期

【关键词】

：

IL-12 B7-1 基因转染细胞 抗肿瘤免疫 癌症 疫苗 IL-12  B7-1  Tumor immunity  Cancer vaccine 

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Objective: To study the synergic effects of IL-12 and B7-1 transfectant on antitumor immunity in vivo. Methods: The retrovirus vector encoding mIL-12 and mB7-1 gene was tranfected into EL-4 thymic lymphoma cells respectively. The cells were used as tumor

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