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应用瞬时收缩末压力—容积线的斜率T-E_(max),与左心室内压发展最人速率dP/dt_(max)进行比较,评价了主动脉内气囊反搏(IABP)对10只狗在体正常及局部缺血心脏心肌收缩性能的影响。T-E_(max)在正常心脏进行IABP时无显著变化(1.97±0.53 vs,1.97±0.56kPa/ml,P>0.05),在缺血心脏进行IABP时显著增加(1.20±0.35 vs 1.41±0.32,P<0.01);而dP/dt_(max),无论在正常(611.85±146.63 vs 503.74±113.70kPa/s,P<0.01)或缺血(336.45±69.54 vs 303.66±70.52,P<0.05)心脏进行IABP时均显著减小。结果表明:IABP对心肌收缩性能的影响与心脏的基础状态有较大关系,IABP仅对缺血心脏有增加心肌收缩性能的作用。T-E_(max)能较恰当地评价狗在体心脏的心肌收缩性能状态,而dP/dt_(max)则有可能低估IABP对心肌收缩性能的影响。
The intra-aortic balloon pump (IABP) was used to evaluate the effects of intra-aortic balloon pump (IABP) on 10 dogs by using the slope T-E max of the end-systolic pressure-volumetric curve and the maximum dP / dt max of left ventricular pressure Effects of systolic performance in normal and ischemic myocardium. T-E max had no significant change (1.97 ± 0.53 vs 1.97 ± 0.56 kPa / ml, P> 0.05) when IABP was performed in normal heart, and was significantly increased in IABP of ischemic heart (1.20 ± 0.35 vs 1.41 ± 0.32 , P <0.01). However, dP / dt max, both in the normal (611.85 ± 146.63 vs 503.74 ± 113.70 kPa / s, P <0.01) or ischemic (336.45 ± 69.54 vs 303.66 ± 70.52, P <0.05) The IABP was significantly reduced. The results showed that the effect of IABP on myocardial contractility was related to the basic state of heart. IABP only had the effect of increasing myocardial contractility. T-E max can be used to evaluate the myocardial systolic performance in dogs, while dP / dt max may underestimate the effect of IABP on myocardial systolic performance.