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目的探讨儿童肺炎支原体(MP)感染致皮肤损害的特点。方法感染患儿506例,采用间接免疫荧光法进行5种病原体联检。观察血清MP-IgM阳性伴皮肤损害患儿的临床资料。结果 506例MP-IgM阳性患儿中,86例在呼吸道感染的基础上伴皮肤损害,其中表现荨麻疹样皮疹36例,红斑或斑丘疹20例,猩红热样皮疹13例,紫癜样皮疹8例,麻疹样皮疹6例,水疱疹3例。阿奇霉紊针静脉滴注3~5d,之后换用罗红霉素口服2~3周,皮疹均在数小时至14d内消失,预后好。结论 MP感染不仅是呼吸道感染的重要病原体,也可致皮肤损害,呼吸道感染并有皮肤损害的病例,要考虑到MP感染的可能。
Objective To investigate the characteristics of skin lesions caused by Mycoplasma pneumoniae (MP) infection in children. Method Infection in children with 506 cases, indirect immunofluorescence method for five kinds of pathogens joint examination. Clinical data of children with MP-IgM positive skin lesions were observed. Results Among the 506 children with MP-IgM positive, 86 patients had skin lesions on the basis of respiratory infection, including 36 cases of hives-like rash, 20 cases of erythema or rash, 13 cases of scarlet fever-like rash and 8 cases of purpuric rash , Measles-like rash in 6 cases, herpes simplex in 3 cases. Azithromycin intramuscular intravenous infusion of 3 ~ 5d, then replaced with roxithromycin oral 2 to 3 weeks, the rash disappeared within a few hours to 14d, the prognosis is good. Conclusion MP infection is not only an important pathogen of respiratory tract infection, but also cause skin damage, respiratory tract infections and skin lesions, taking into account the possibility of MP infection.