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目的:探讨超声心动图评价心内膜弹力纤维增生症患儿治疗前、后左心功能的价值。方法:心内膜弹力纤维增生症患儿30例,经合理治疗后心功能均明显改善。应用超声心动图常规左室长轴M型测量患儿治疗前、后左室射血分数及短轴缩短率,应用脉冲多普勒和组织多普勒测量二尖瓣口舒张早期血流频谱峰值速度E、二尖瓣口舒张末期血流频谱峰值速度A,计算E/A值、等容舒张时间(isovolumic relaxation time,IVRT)和二尖瓣环舒张早期峰值运动速度e(Ve)、舒张晚期峰值运动速度a(Va),并进行比较。结果:24例治疗前IVRT为(0.09±0.01)s,E/A值为1.2±0.6,治疗后IVRT为缩短(0.08±0.02)s,E/A值增高为1.6±0.4,治疗前、后比较差异有统计学意义(P<0.05);6例治疗前二尖瓣口血流频谱表现为假性正常化,治疗前、后IVRT,E/A值比较差异无统计学意义(P>0.05)。结论:超声心动图可用于评价心内膜弹力纤维增生症患儿左心功能。
Objective: To evaluate the value of echocardiography in evaluating the left ventricular function in children with endocardial fibroelastosis before and after treatment. Methods: 30 cases of endocardial fibroelastosis in children, after reasonable treatment were significantly improved cardiac function. The left ventricular ejection fraction and short axis shortening before and after treatment of children with conventional left ventricular long-axis M-mode measurement using echocardiography were measured. Pulmonary Doppler and Tissue Doppler were used to measure the peak value of mitral early diastolic blood flow Velocity E, peak velocity of mitral end-diastolic flow spectrum peak velocity A, E / A value, IVRT and peak early diastolic mitral annulus velocity e (Ve), late diastole Peak velocity a (Va), and compared. Results: Before treatment, IVRT was (0.09 ± 0.01) s, E / A was 1.2 ± 0.6, IVRT was shortened (0.08 ± 0.02) s and E / A was increased to 1.6 ± 0.4 (P <0.05). Before 6 months of treatment, mitral inflow velocity spectrum showed pseudo-normalization. There was no significant difference in IVRT and E / A before and after treatment (P> 0.05) ). Conclusion: Echocardiography can be used to evaluate left ventricular function in children with endocardial fibroelastosis.