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目的分析妊高征患者凝血系列各指标及血小板水平的变化。方法选择妊高征患者及正常孕妇各50例,分别检测两组凝血酶原时间(PT)、部分活化凝血酶原时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)及血小板(PLT)水平的指标,并将两组指标进行对比分析。结果妊高征患者PT及PLT水平明显低于正常孕妇组,APTT、TT、FIB水平明显高于正常孕妇组。结论妊高征孕妇可同时存在凝血异常及血小板减少,且二者变化存在一定相关性。
Objective To analyze the changes of coagulation index and platelet in patients with pregnancy induced hypertension. Methods Fifty patients with PIH and 50 normal pregnant women were enrolled in this study. Prothrombin time (PT), partial activated prothrombin time (APTT), fibrinogen (FIB), thrombin time (TT) and platelet (PLT) level indicators, and two sets of indicators for comparative analysis. Results The levels of PT and PLT in patients with PIH were significantly lower than those in normal pregnant women, and the levels of APTT, TT and FIB were significantly higher than those in normal pregnant women. Conclusion Pregnancy-induced hypertension can present both coagulation abnormalities and thrombocytopenia, and there is a certain correlation between the two.