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[目的]了解南通市健康人群脊髓灰质炎免疫现状及脊灰疫苗(OPV)免疫成功率。[方法]健康人群抗体水平监测按照5月龄~、1~2岁、3~4岁、5~6岁、7~14岁、15~19岁、20岁~7个年龄组,每个年龄组各随机抽取50名健康人群进行观察。免疫成功率监测选择2月龄未服过OPV的53名儿童作为观察对象,比较脊灰基础免疫前及完成脊灰疫苗(OPV)全程免疫(3次)后抗体水平并脊灰免疫成功率。[结果]①被调查健康人群脊灰Ⅰ、Ⅱ、Ⅲ型抗体阳性率均为100%,抗体几何平均滴度(GMT)分别为1︰410.96、1︰372.22、1︰279.86。②完成脊灰疫苗(OPV)全程免疫(3次)后儿童脊灰Ⅰ、Ⅱ、Ⅲ型免疫成功率分别为96.23%、100%、98.11%。[结论]南通市健康人群脊灰抗体阳性率和GMT均高,已对脊髓灰质炎形成较好的免疫屏障。我市脊灰疫苗的接种质量较好,儿童OPV的免疫成功率维持在较高水平。
[Objective] To understand the status quo of polio immunity and the success rate of polio vaccine (OPV) in healthy population in Nantong City. [Method] The antibody levels in healthy population were monitored according to the age of 5 months, 1 to 2 years, 3 to 4 years, 5 to 6 years, 7 to 14 years, 15 to 19 years, 20 to 7 years of age, Group randomly selected 50 healthy people for observation. Surveillance on Immune Survival Rate Fifty-three children who did not take OPV at 2 months of age were enrolled in the study. The antibody levels and the success rate of polio immunization before and after the completion of polio-based immunization (3 times) and complete polio-based immunization (OPV) were compared. [Results] ① The positive rates of type Ⅰ, Ⅱ and Ⅲ antibodies of poliovirus in the healthy population were all 100%. The geometric mean titers of antibodies (GMT) were 1︰410.96,1︰372.22,1︰279.86 respectively. ② The success rates of type I, type II and type III immunization of children with complete poliovirus (OPV) immunization (3 times) were 96.23%, 100% and 98.11% respectively. [Conclusion] The positive rate of poliovirus and the GMT of healthy population in Nantong City are high, which have formed a good immune barrier to polio. The polio vaccination quality in our city is good, the success rate of children’s OPV immunization is maintained at a high level.