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目的探讨早期行颅骨修补术对颅脑损伤患者神经功能及预后的影响。方法选择2015年6月—2016年6月收治的56例颅脑损伤患者作为研究对象,均已进行颅脑损伤去骨瓣减压术。采用随机数表法将其分为对照组和观察组各28例。观察组在去骨瓣减压术后3个月内行颅骨修补术,对照组在去骨瓣减压术后3~6个月行颅骨修补术。比较两组美国国立卫生研究院卒中量表评分(National Institute of Health stroke scale,NIHSS)、并发症以及预后情况。计量资料比较采用t检验,计数资料比较采用χ~2检验,P<0.05为差异有统计学意义。结果与治疗前相比,治疗后两组NIHSS评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05);随访半年,观察组预后情况优于对照组,差异有统计学意义(P<0.05)。结论早期行颅骨修补术对颅脑损伤患者神经功能及预后均具有明显的改善作用,可减少并发症发生,提高患者术后生活质量。
Objective To investigate the effect of cranioplasty on neurological function and prognosis in patients with craniocerebral injury. Methods Fifty-six patients with craniocerebral injury who were treated in our hospital from June 2015 to June 2016 were enrolled in this study. All patients underwent craniocerebral injury with decompressive craniectomy. Using random number table method, it was divided into control group and observation group, 28 cases each. In the observation group, skull repair was performed within 3 months after decompressive craniectomy, while in the control group, skull repair was performed 3 to 6 months after decompressive craniectomy. Two National Institutes of Health Stroke Scale scores (NIHSS) were compared for complication and prognosis. Measurement data were compared using t test, count data were compared using χ ~ 2 test, P <0.05 for the difference was statistically significant. Results Compared with those before treatment, the NIHSS scores of the two groups decreased after treatment, and the observation group was lower than the control group, the difference was statistically significant (P <0.05); the incidence of complications in the observation group was lower than that of the control group (P <0.05). The follow-up of six months showed that the prognosis of the observation group was better than that of the control group (P <0.05). Conclusions Early skull repair can significantly improve the neurological function and prognosis of patients with craniocerebral injury, reduce the incidence of complications and improve the postoperative quality of life.