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锌指蛋白A20是具有特征性锌指结构的一类蛋白,它参与机体炎症反应及细胞凋亡等重要的生命过程。近来研究表明,A20在多种类型的肿瘤细胞和组织中异常表达,可能与肿瘤细胞的增殖、耐药和血管形成等相关,但具体作用机制不明。深入研究A20在恶性肿瘤发生发展中的作用及其机制,对恶性肿瘤的诊断、治疗和预后判断均有重要的临床意义。
Zinc Finger Protein A20 is a type of protein that has a characteristic zinc finger structure and is involved in important life processes such as inflammation and apoptosis. Recent studies have shown that A20 in many types of tumor cells and tissues abnormal expression may be related to tumor cell proliferation, drug resistance and angiogenesis, but the specific mechanism of action unknown. In-depth study of A20 in the occurrence and development of malignant tumors and its mechanism, the diagnosis of malignant tumors, treatment and prognosis have important clinical significance.