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目的 评价彩色多普勒血流显像(CDFI)及脉冲多普勒(PD)检测恶性滋养细胞肿瘤的早期诊断疗效观察及判断疾病转归的应用价值。方法 应用CDFI及PD检测恶性滋养细胞肿瘤患者32例,并以正常妊娠20例作对照。结果 CDFI恶性滋养叶肿瘤表现为丰富而敏感的彩色血流,PD为低速的动静脉血流。正常妊娠为不甚敏感的点状或多条状的不规则血流,PD为单相或双相的低速动脉血流。阻力指数(RI)显著性差异(P<0.01)。结论 CDFI和PD检测可做为一种新的方法,不仅可对滋养叶细胞肿瘤作出早期诊断,亦可用于观察化疗效果,判断疾病的转归。
Objective To evaluate the early diagnosis of malignant trophoblastic tumor by color Doppler flow imaging (CDFI) and pulsed Doppler (PD), and to evaluate the value of disease prognosis. Methods 32 cases of malignant trophoblastic tumor were detected by CDFI and PD, and 20 cases of normal pregnancy were used as control. Results CDFI malignant trophoblastic tumor manifested as rich and sensitive color flow, PD for low velocity arteriovenous flow. Normal pregnancy is not sensitive to the punctate or multiple irregular blood flow, PD is single-phase or biphasic low-speed arterial blood flow. Resistance index (RI) significant difference (P <0.01). Conclusions CDFI and PD can be used as a new method not only to make early diagnosis of trophoblastic tumor but also to observe the effect of chemotherapy and to judge the outcome of the disease.