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目的:观察和评价地榆升白片预防抗结核药物致白细胞减少的效果。方法:88例肺结核患者分为两组,两组均采用标准短程化疗方案(2HREZ/4HR)进行抗结核治疗,其中治疗组在抗结核治疗的基础上加用地榆升白片,口服,每次4片,每日3次,观察地榆升白片预防患者抗结核治疗白细胞减少症的效果。结果:治疗组白细胞减少发生率与对照组比较有显著性差异(P<0.05),两组III~IV白细胞减少无显著性差异(P>0.05),两组痰涂片转阴率比较无显著性差异(P>0.05)。结论:地榆升白片可有效预防肺结核患者抗结核药物致白细胞减少。
Objective: To observe and evaluate the effect of Diyu Shengbai Tablets in preventing leukopenia caused by antituberculosis drugs. Methods: Eighty-eight patients with tuberculosis were divided into two groups. Both groups were treated with standard short-course chemotherapy (2HREZ / 4HR) for antituberculous therapy. The treatment group was given Ulmus officinalis L 4 tablets 3 times a day to observe the effect of Di Yu Sheng Bai Tablet in patients with anti-TB treatment of leukopenia. Results: The incidence of leukopenia in the treatment group was significantly lower than that in the control group (P <0.05), and there was no significant difference in the III ~ IV leukopenia between the two groups (P> 0.05). There was no significant difference in the sputum smear negative conversion rate between the two groups Sex differences (P> 0.05). Conclusion: Di Yu Sheng Bai tablets can effectively prevent tuberculosis patients anti-TB drug induced leukopenia.